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2. Water Conservation Surprisingly, using a car spray washer can be more water-efficient than traditional washing methods. A pressure washer typically uses less water to achieve a thorough clean. Many models are designed to provide powerful cleaning with minimal water usage, making them an eco-friendly option.
In addition to oral dosage forms, HPMC is also utilized in topical applications. It serves as a thickening agent in creams and gels, providing an ideal texture and stability for dermatological products. Furthermore, it is employed in the formulation of ophthalmic products, where its gel-forming properties enhance the retention time of the medication in the eye, thus improving delivery and efficacy.
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2. Degree of Substitution The degree of substitution (DS) refers to the average number of hydroxyl groups in the cellulose molecule that have been replaced by hydroxypropyl and methyl groups. A higher DS typically results in increased solubility and altered physical properties, which can also impact density. As more hydroxyl groups are substituted, the overall density may decrease due to changes in hydrogen bonding and molecular interactions.
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One of the primary differences between HPMC and methylcellulose is their molecular weight. HPMC has a higher molecular weight than methylcellulose, which means it can form more extensive and stronger gels. Therefore, HPMC is often used in applications where high viscosity and gel strength are required, such as in pharmaceutical tablet coatings and sustained-release formulations.